The following description was prepared by William Gross:
From earliest times, man has tried to protect himself from misfortune by the use of objects that he considered holy or otherwise (e.g., magically) potent. Amulets and talismans are items generally worn around the neck or wrist, carried in a pocket or purse or hung on a wall. They are meant to protect or aid those who carried or wore them. The Hebrew word for amulet, kame‘a, has the root meaning "to bind". Jewish amulets are usually comprised of texts (either letters or graphic symbols) that are inscribed on some sort of material; some may also contain plant matter or precious stones. The texts of amulets usually include holy names that are believed to have the ability to affect reality, along with incantations summoning angels or other magical powers. For the most part, an amulet has a specific purpose: to ease childbirth, facilitate recovery from illness, improve one’s livelihood, and so on, but in the modern world many are also made for general protection.
This is a combination of amulet and Shiviti originally printed in Jerusalem or Poland and now copied in Warsaw. The original print is also in the Gross Family collection. But all of such imaged pages are grounded in the first appearance of the image combining the angel and kabbalistic hand in in Lviv in 1855. The image originated in Europe but was later ascribed to Eretz Israel and continued to be printed in both places. In the inscription, it is recorded that this was printed "Peh Shin". It would seem that this means Pa'am Sheniyah, or for a second time. It is very likely that this refers to this being a copy of the printed Shivitit from the beginning of the 1860s, 027.011.055.
Since letterpress printing was not done in Safed between the years 1836 - 1863 or between 1866 - 1876, this was likely done by wood block in the interim between 1863 and 1866 by the printer Dov Be'er Kara who was active there at this time. While this central image of the angel and hand was originally against plague, here it is indicated as protection against plague but also against fire. Its continual later use was almost entirely as a birth amulet and continued to be used as such well into the 20th century in many places. This version is nicely printed in gold ink.
The wood carver who made this amulet also made the woodcut center of the Gross Family Collection Safed amulet from 1864 - 1866, 027.011.045.