Four people wearing masks are depicted. Three of them are men who are wearing long pointed hats. The scene most likely depicts Purim celebration contemporary to the manuscript's creator.
The text is inscribed in a square Italian script in 19 text panels, in 20 columns containing 13 lines each. Panel no. 16 is an exception and contains 2 columns: one of them is the column listing the names of Haman's ten sons inscribed in the most populat layout.
On the opening section, three library stamps are visible.
On the opening part of the scroll there is a Hebrew inscription:
הגביר כהר שמואל יצו בכה הגביר המרומם הר' יצחק נטף יצו יזייא
Icchak Nataf is the author of ושבועתו ליצחק
published in Livrono in 1825 (https://www.hebrewbooks.org/9053)
Carlo Bernheimer, Catalogo dei manoscritti orientali della Biblioteca Estense, Roma 1960, 88, object 8.